Identification of flavonoids by HPLC-MS in fruit waste of Latin America: A systematic review


  • Noemí León-Roque Universidad Nacional Pedro Ruiz Gallo, Facultad de Ingeniería Química e Industrias Alimentarias, Grupo de Investigación para la Ciencia y Tecnología de Alimentos Funcionales. Juan XXIII 391, Lambayeque
  • Blanca Margarita Romero Guzmán Universidad Nacional Pedro Ruiz Gallo, Facultad de Ingeniería Química e Industrias Alimentarias, Grupo de Investigación para la Ciencia y Tecnología de Alimentos Funcionales. Juan XXIII 391, Lambayeque .
  • Jimy Oblitas Universidad Privada del Norte, Facultad de Ingeniería, Vía de Evitamiento s/n Cuadra 15, Cajamarca.
  • Davy W. Hidalgo-Chávez Universidade Federal Rural do Rio de Janeiro, Programa de Pós-graduação em Ciência e Tecnologia de Alimentos, km 07, Zona Rural, BR-465, Seropédica.


Palabras clave:

flavonoids, High Performance Liquid Chromatography-Mass Spectrometry, fruit waste, detection technique, Latin America


Fruit waste is rich in phenolic compounds, including flavonoids with pharmacological potential for health, nutraceutical and technological properties. To characterize them, High Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) was used, used for its high separation efficiency by HPLC and structural information from MS, a technique that allows analyzing a wide range of analytes in plant matrices. This study aims was to perform a systematic analysis based in SCOPUS of scientific productions of studies on techniques for detection and identification of flavonoids by HPLC-MS in fruit waste available in Latin America, between the years 2010-2022. Thus, the countries with the highest scientific production are Brazil (58.9%), Mexico (16.1%), Chile (9.2%), Argentina (7.1%) and Colombia (3.8%). There were also studies in collaboration with researchers from the USA and Europe. A total of 15.1% of the studies used HPLC-MS for determining these compounds, generally related to by-products of native or non-traditional fruits. It is known that agro-industrial waste matrices are chemically complex, being necessary analytical techniques such as HPLC-MS, which awakens interest for their study and the possibility of being isolated from vegetable by-products such as fruits. This is a green technology alternative to achieve sustainable use of this waste and be exploited by the food industry.

Biografía del autor/a

Noemí León-Roque, Universidad Nacional Pedro Ruiz Gallo, Facultad de Ingeniería Química e Industrias Alimentarias, Grupo de Investigación para la Ciencia y Tecnología de Alimentos Funcionales. Juan XXIII 391, Lambayeque





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Cómo citar

León-Roque , N., Romero Guzmán, B. M., Oblitas , J. ., & Hidalgo-Chávez, D. W. . (2023). Identification of flavonoids by HPLC-MS in fruit waste of Latin America: A systematic review. Scientia Agropecuaria, 14(1), 153-162.



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