“La vitamina D”

Authors

  • Abhel Calderón-Peña Universidad Nacional de Trujillo
  • Cinthya Aspajo-Villalaz Universidad Nacional de Trujillo

Abstract

La vitamina D tiene un rol importante en la homeostasis del calcio/fosfato, respuesta inmune, proliferación y diferenciación celular, procesos cognitivos. Sin embargo, su aporte deficiente o adecuado puede llevar al desarrollo de patologías o no. El receptor de vitamina D (VDR), perteneciente a la familia de receptores nucleares, desencadena la expresión o la transrepresión de genes involucrados con el metabolismo. El objetivo de esta investigación bibliográfica es mostrar los conocimientos actuales acerca de la vitamina D, comprender el mecanismo celular de la activación del receptor de vitamina D y los eventos fisiológicos y patológicos que se desencadenan cuando existe un adecuado e inadecuado aporte en la dieta. La vitamina D es una hormona que posee múltiples e importantes funciones en el organismo humano y animal. Podemos deducir que la mayor fuente de vitamina D en el organismo se encuentra en la síntesis en la piel, por el contrario, existen poblaciones en las cuales no se produce adecuadamente esta, es así que existe la necesidad de suplementar la dieta con vitamina D. La vitamina D tiene mucha influencia en el sistema inmune, proliferación y diferenciación celular, metabolismo y funciones cognitivas que, cuando se produce una deficiencia de esta vitamina suele desencadenar algunos fenómenos patológicos.

 

Palabras clave: vitamina D, receptor de vitamina D.

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Published

2019-03-04

How to Cite

Calderón-Peña, A., & Aspajo-Villalaz, C. (2019). “La vitamina D”. REBIOL, 38(2), 75-87. Retrieved from https://revistas.unitru.edu.pe/index.php/facccbiol/article/view/2278

Issue

Section

ARTÍCULOS DE REVISIÓN / OPINIÓN